If you're addicted, you may feel unable to quit using the drug.
Dependence is when your body learns to depend on a drug.
Histamine-1 receptors are also found in the brain and spinal cord, and stimulation of these receptors makes you more awake and alert.
Stimulation of these receptors can lead to conditions such as a skin rash or inflammation, a narrowing of the airways (bronchoconstriction), hay fever, or motion sickness.It can occur without addiction, but it often accompanies addiction.If you become dependent on a drug, you may need a higher dose to achieve the desired effect (tolerance), or there may be physical or psychological effects when the drug is stopped (withdrawal).The American Society of Anesthesiologists defines the continuum of sedation as follows: Prior to any oral sedation methods being used on a patient, screening must be done to identify possible health concerns.
Before using sedation, doctors try to identify any of the following that may apply: known drug allergies and sensitivities, hypertension, heart defects, kidney disease, other allergens, such as latex allergy, history of stroke or transient ischemic attack (TIA) (certain oral sedation methods may trigger a TIA), neuromuscular disorders (such as muscular dystrophy), or a current list of medications and herbal supplements taken by the patient.Aside from the suppression of respiration, risks also include unintended levels of sedation, postoperative somnolence, aspiration, To avoid sedation risks, care providers conduct a thorough pre-sedation evaluation and this process includes pre-sedation history and physicals with emphasis on the determining characteristics that indicate potential risks to the patient and potential difficult airway management.